POLYNUCLEOTIDES ENCOURAGE COLLAGEN & ELASTIN PRODUCTION 

London Dermatology | 5 February 2025

Innovative substances called polynucleotides are transforming the way we think about skin renewal. They provide a powerful means to get glowing, youthful skin and are quickly rising to the top of the list of therapies.

Nucleic acids are the building blocks of physiologically active compounds called polynucleotides. These substances are extremely helpful in skincare since they are essential for cellular regeneration and repair. You may have seen people refer to polynucleotides as the “Salmon Sperm” treatment on Instagram and TikTok. They are taken from natural sources like salmon DNA.

The advantages are numerous and genuinely life-changing. Polynucleotides greatly increase skin hydration levels and improve the skin’s capacity to retain moisture. They also promote the formation of collagen, improve skin hydration, and improve overall skin texture. Furthermore, they can help repair damaged skin and encourage the formation of new tissue, which helps lessen some of the harm brought on by UV radiation and sun damage. For anyone wishing to maximise and preserve the general health of their skin, they are a true all-arounder therapy. 

Although Profhilo and polynucleotides are both used to rejuvenate skin, their composition and functions are different. While Profhilo employs hyaluronic acid to improve the quality and structural integrity of skin, polynucleotides concentrate on cellular regeneration and hydration using a nucleotide-based method. Large molecules called polynucleotides are composed of nucleotides, which are the building blocks of DNA. They improve blood flow and encourage tissue healing, which results in skin that looks healthier.

Although polynucleotides can be injected into any part of the body’s skin, most individuals choose to use them beneath the eyes because this is the first place on the face where you’ll detect signs of ageing and possible skin laxity. Because polynucleotides promote the formation of collagen and elastin, which will help to increase the thickness and health of the skin and eventually lessen the appearance of dark circles and under-eye hollows, they’re a great substitute for tear-trough fillers, which only add volume.

It can be used on the backs of the arms, stomach, and décolletage. Lately, we’ve been seeing people utilise it to treat their knees. Polynucleotides are an excellent choice for tightening and revitalising any part of the body where skin laxity is present.